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Anti-Iduna/RNF146 Antibody

Anti-Iduna/RNF146 Antibody

Item no.	75-233
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, ICC
Clone	N201/35
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase RNF146 (EC 2.3.2.27) (Iduna) (RING finger protein 146) (RING-type E3 ubiquitin transferase RNF146)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Iduna/RNF146
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	40 kDa
Manufacturer - Research Area	Cell Signaling, Wnt Signaling
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-359 (full-length) of mouse Iduna (accession number Q9CZW6) produced recombinantly in E. Coli
Immunogen Species	Mouse
Description	Our Anti-Iduna/RNF146 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N201/35. It detects mouse and rat Iduna/RNF146, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description	E3 ubiquitin-protein ligase RNF146, RING finger protein 146 or Iduna is encoded by the gene RNF146. Iduna is a ubiquitin protein ligase that is involved in ubiquitination and degradation. It is thought to be involved with diverse processes including DNA repair, activation of the Wnt signaling pathway, protection from DNA damage induced cell death. Iduna is found in many tissues including brain, heart, spleen, kidney and liver.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Iduna/RNF146 mouse monoclonal primary antibody from hybridoma clone N201/35. It is great in ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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