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Anti-RBM17/SPF45 Antibody

Anti-RBM17/SPF45 Antibody

Item no.	75-234
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Oncology Antibodies Immunohistochemistry Immunocytochemistry Primary Antibodies By Organ Breast Cancer Immunoblot
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N219/5
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	RBM17/SPF45
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	45-52 kDa
Manufacturer - Research Area	Cell Signaling, Neurogenesis and Development
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 100-200 of human RBM17 (accession number Q96I25) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-RBM17/SPF45 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N219/5. It detects human, mouse, and rat RBM17/SPF45, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	RNA-Binding Motif Protein 17 or Splicing factor 45 is encoded by the gene RBM17. RBM17 is a component of the spliceosome complex and displays catalytic activity during mRNA splicing. RBM17 is involved in alternative splicing, resulting in different isoforms of a gene. RBM is also thought to play a role in DNA repair (Red: Chaouki et al 2006) RBM17 is widely expressed in the nucleus and important for development. Diseases associated with this gene include sickle cell anemia and forms of Ataxia 1.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity reported
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our RBM17/SPF45 mouse monoclonal primary antibody from hybridoma clone N219/5. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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