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Anti-GFAP Antibody

Anti-GFAP Antibody

Item no.	75-240
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Development Antibodies Immunohistochemistry Immunocytochemistry Primary Antibodies Immunoblot Microglia Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC, ICC
Clone	N206A/8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Guinea Pig, Drosophila
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Glial fibrillary acidic protein (GFAP)
Shipping Condition	Cool pack
Available
Specificity	Drosophila, Guinea Pig, Human, Mouse, Polar Bear, and Rat
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	GFAP
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	50 kDa
Manufacturer - Research Area	Cell Markers, Glial and Schwann Cell Markers, Astrocyte Markers
Expiration	24 months from date of receipt
Immunogen	Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession number P14136)
Immunogen Species	Human
Description	Our Anti-GFAP mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N206A/8. It is KO validated, detects human, mouse, and rat GFAP, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Glial fibrillary acidic protein (GFAP) is an intermediate filament with many different isoforms, and acts as a structural protein in the cytoskeleton. It is expressed in astrocytes in brain and is often used as an astrocyte marker. GFAP is belived to be involved in many CNS processes including cell communication and mitosis. GFAP has been found to be involved in Alexander disease and Wernicke's encephalopathy.
Clonality	Monoclonal
Manufacturer - Specificity	Cross-reacts with GFAP-R416W and other GFAP mutant proteinsDoes not cross-react with other proteins (based on KO validation results)
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Dilution Range: WB	1:1000
Dilution Range: IHC	1:500
Dilution Range: ICC	1:500
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our GFAP mouse monoclonal primary antibody from hybridoma clone N206A/8. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 8/28/2025

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