Anti-TRIP8b (Exon 1b) Antibody

TRIP8b (exon 1b)

Shipped on ice packs

70 kDa

24 months from date of receipt

Rat

PEX5-related protein, Peroxisomal Biogenesis Factor 5 Like, TPR-containing Rab8b-interacting protein or TRIP8b is encoded by the gene Pex5l. It is a member of the peroxisomal targeting signal receptor family. TRIP8b is a cytoplasmic accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. TRIP8b interacts with the carboxyl-terminal region of HCN channels and regulates their cell-surface expression to the dendrites in many types of neurons. TRIP8b plays a role in regulation of HCN channel cyclic nucleotide kinetics. TRIP8b is expressed in the brain. Diseases associated with PEX5L include Rhizomelic Chondrodysplasia Punctata, Type 5 and Rhizomelic Chondrodysplasia Punctata, Type 2.

Specific for exon 1b(does not react with TRIP8b isoforms containing exons 1a, 2 or 4)

Purified by Protein A chromatography

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Brain

We produce our TRIP8b (exon 1b) mouse monoclonal primary antibody from hybridoma clone N212A/34. It is great in ICC, WB and is purified by Protein A chromatography.