Comparison

Anti-TRAAK Potassium Channel Antibody

Item no. 75-433
Manufacturer Antibodies Incorporated
Amount 100 uL
Category
Type Antibody Monoclonal
Format Liquid
Applications IHC, ICC
Clone N445/27
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Potassium channel subfamily K member 4 (TWIK-related arachidonic acid-stimulated potassium channel protein) (TRAAK)
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
TRAAK potassium channel
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
43 kDa
Manufacturer - Research Area
Ion Channels and Modulators, K+ Channels
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 256-398 (cytoplasmic C-terminus) of mouse TRAAK (accession number O88454) produced recombinantly in E. Coli
Immunogen Species
Mouse
Description
Our Anti-TRAAK potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N445/27. It detects mouse and rat TRAAK potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Target Description
Potassium two pore domain channel subfamily K member 4 is encoded by the gene KCNK4. KCNK4 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK4 homodimerizes and functions as an outwardly rectifying channel. KCNK4 is regulated by polyunsaturated fatty acids, temperature, and mechanical deformation of the lipid membrane. KCNK4 is expressed in the brain, spinal cord, and eye. Diseases associated with KCNK4 include Facial Dysmorphism, Hypertrichosis, Epilepsy, Intellectual/Developmental Delay, and Gingival Overgrowth Syndrome.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with TREK1/KCNK2
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our TRAAK potassium channel mouse monoclonal primary antibody from hybridoma clone N445/27. It is great in IHC, ICC and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 uL
Available: In stock
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