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ARHGEF7 Antibody (C-Term) [ApR05015G]

ARHGEF7 Antibody (C-Term) [ApR05015G]

Item no.	LBI-APR05015G
Manufacturer	Leading Biology
Amount	100 ul
Category	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Western Blot ELISA Primary Antibodies small GTPases Rho Subfamily
Type	Antibody
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85, ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Available
Manufacturer - Type	Polyclonal Antibodies
Manufacturer - Category	Abs-G
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	90012
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality ARHGEF7 Antibody (C-Term) [ApR05015G].
Manufacturer - Specificity	This ARHGEF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 654-688 amino acids from human ARHGEF7.
Cellular localization	Cell junction, focal adhesion. Cell projection, ruffle. Cytoplasm, cell cortex Cell projection, lamellipodium. Note=Detected at cell adhesions. A small proportion is detected at focal adhesions
Gene Name	ARHGEF7
Function	Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Dilution	WB-1:2000
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/16/2025

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