Anti-Prolylcarboxypeptidase (PRCP) (13920) - 100μl

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Next Day 2 - 8°C

Prolylcarboxypeptidase (PRCP) cleaves C-terminal amino acids linked to a proline if proline has aprotected amino group or is part of a peptide chain. As a lysosomal enzyme, it has a sharp acidpH optimum with shorter substrates, but with longer peptides, some activity is retained at neutralpH. PRCP is found in a variety of human cells, including white blood cells, fibroblasts, andendothelial cells, and organs such as kidney and lung, and it is excreted in urine. Becauseangiotensins II and III share a common C terminus (-pro-phe-OH), and are substrates for PRCP, prolylcarboxypeptidase has also been referred to as angiotensinase C.

PBS, 0.05% sodium azide, 50% glycerol.