Anti-ß-Defensin-3 [Polyclonal] - 100 µg

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Next Day 2 - 8°C

Human beta-defensin-3 (hBD-3) is a unique, non-hemolytic antimicrobial peptide originally isolated from human psoriatic scales and cloned from keratinocytes. This potent peptide exhibits salt-insensitive, broad-spectrum antimicrobial activity against a wide range of pathogenic microbes, including multi-drug resistant S. aureus and vancomycin-resistant Enterococcus faecium. Found in keratinocytes and airway epithelial cells, hBD-3 expression can be induced by TNF-alpha and bacterial contact, suggesting its crucial role in the innate epithelial defense against infections in tissues like the skin and lungs (e.g., in conditions like cystic fibrosis).

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