Comparison

Anti-Atg2A Antibody (23001) - 100 µg

Item no. LEIN-23001-100ug
Manufacturer Leinco Technologies
Amount 100 ug
Category
Type Antibody Primary
Applications WB, IF, ICC
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Shipping Condition Cool pack
Available
Manufacturer - Applications
WB, ICC/IF
Manufacturer - Category
Antibody Products>Autophagy Antibodies|Products
Manufacturer - Targets
Atg2A
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This antibody is stable for at least one (1) year at -20°C.
Product Description
Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Two human Atg2 homologs (Atg2A, Atg2B) are critical for autophagosome formation as silencing of both results in the accumulation of unclosed autophagic structures. Starvation-induced autophagy targets Atg2A to the initiation site of autophagosome biogenesis, where it associates with DFCP1, WIPI-1, and other autophagy- related proteins. Atg2 proteins also function in lipid droplet metabolism as depletion of both Atg2A and AtgB results in changes in the size, number, and distribution of lipid droplets. An increase in Atg2A expression during etoposide- and doxorubicin-induced apoptosis suggests that Atg2A may be a useful indicator of topoisomerase II inhibitor-mediated apoptosis.
Manufacturer - Research Area
Autophagy
Concentration
1.0 mg/ml
Formulation
PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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