Comparison

Anti-HIF1α Antibody (34039) - 100 µg

Item no. LEIN-34039-100ug
Manufacturer Leinco Technologies
Amount 100 ug
Category
Type Antibody Monoclonal
Applications WB, IF, IHC, ICC, ELISA
Clone ESEE122
Specific against other
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Cool pack
Available
Manufacturer - Applications
ELISA, IHC, WB, ICC/IF
Manufacturer - Category
Antibody Products>Cancer Research Antibodies|Products
Manufacturer - Targets
HIF1α
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This antibody is stable for at least one (1) year at -20°C. Store in appropriate aliquots to avoidmultiple freeze-thaw cycles.
Product Description
Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor that regulates the transcription of a broad range of genes that facilitate responses to hypoxia including genes that regulate angiogenesis, erythropoiesis, cell cycle, metabolism, and apoptosis. HIF-1 is comprised of two subunits, HIF-1alpha and HIF-1beta. The widely expressed HIF-1alpha is degraded rapidly in normoxic cells by the ubiquitin/proteasomal pathway. HIF-1alpha is proline hydroxylated leading to a conformational change that promotes binding to the von Hippel Lindau protein (VLH)-E3 ligase complex; ubiquitination and proteasomal degradation follows.
Manufacturer - Research Area
Cancer Research
Concentration
Lot Specific
Formulation
PBS, pH 7.4; 50% glycerol, 0.09% sodium azide. Purified by Protein G affinity chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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