Anti-Canine PD-1 [Clone JC053] - 100 µg

Antibody Products>Cancer Research Antibodies|Products

Next Day 2 - 8°C

Each year, thousands of dogs are diagnosed with cancer. Canine cancers bear many of thehallmarks of human cancers including tissue location, tumor progression, and response tochemotherapy and radiation. Unfortunately, canine lymphocyte populations are not as welldefined as human lymphocytes, and reagents that target immune checkpoint pathways are notyet widely available for veterinary research. Interruption of the programmed death 1 (PD-1) /programmed death ligand 1 (PD-L1) pathway is an established and effective therapeutic strategyin human oncology and may be effective for treating canine cancers as well.

Lot Specific

PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells.