Anti-Transglutaminase-2 [7D2] - 100 µg

Antibody Products>Enzymes and Enzyme Inhibitor Antibodies|Primary Monoclonal Antibodies|Products

Next Day 2 - 8°C

Transglutaminase 2 (TG2) is a multi- domain, multi-functional enzyme that post-translationally modifies proteins by catalyzing the formation of inter- molecular isopeptide bonds between glutamine and lysine side-chains. It plays a role in diverse biological functions, including extracellular matrix formation, integrin mediated signaling, and signal transduction involving 7- transmembrane receptors. While some of the roles of TG2 under normal physiological conditions remain obscure, the protein is believed to participate in the pathogenesis of several unrelated diseases including celiac sprue, neurodegenerative diseases, and certain types of cancer.

Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.