Comparison

Anti-HER2/ErbB2 Rabbit mAb

Item no. PTM-5068
Manufacturer PTM Biolabs
Amount 100 ul
Category
Type Antibody Monoclonal
Format Lyophilized powder
Applications IHC-P
Clone JRMR-121
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias MLN 19, p185erbB2
Shipping condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
HER2/ErbB2
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Manufacturer - Research Area
Cancer, Cell Biology
Product description
Anti-ErbB2/HER2 Rabbit mAb (Clone JRMR-121)
Purification Method
Protein A purified
Constituents
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Stability
Stable for 12 months from date of receipt/reconstitution.
Background
The ErbB family of receptor tyrosine kinases, consisting of the epidermal growth factor (EGF)1 receptor ErbB1, ErbB2/ Neu, ErbB3, and ErbB4, binds a large group of ligands, the EGF-related peptides. Upon ligand-induced dimerization, the receptors autophosphorylate on specific tyrosine residues in their cytoplasmic tails. These residues provide docking sites for hosphotyrosine binding, cytoplasmic signaling molecules hat activate numerous intracellular signaling pathways.
Cellular Localization
Plasma membrane

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
available

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