Anti-SUMO-2/3 Mouse mAb (C-terminal)

Primary Antibodies

SUMO-2, SUMO-3

18

Anti-SUMO-2/3 Mouse mAb

Anti-SUMO-2/3 Mouse mAb recognizes endogeneous level of SUMO-2/3 protein.

Unmodified

Recombinant Monoclonal

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It is a ubiquitin-like protein and functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin, which is primarily associated with targeting proteins for proteasomal degradation, SUMO2 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants encoding different isoforms have been characterized.