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Anti-Septin 2 Mouse mAb

Anti-Septin 2 Mouse mAb

Item no.	PTM-5434
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized powder
Applications	WB, IHC-P
Clone	13059
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
Citations	Yaxin Xu, et al. Chemical proteomics reveals Nε-fatty-acylation of septins by Rho Inactivation Domain (RID) of the Vibrio MARTX toxin to alter septin localization and organization. MOLECULAR & CELLULAR PROTEOMICS, 2024. https://www.sciencedirect.com/science/article/pii/S1535947624000203.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	NEDD-5, SEPTIN2, SEPT2
Shipping condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	Septin 2
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Cell Biology
Product description	SEPT2 can hetero-oligomerize with SEPT6 and SEPT7 to form filaments. SEPT2 interacted with SEPT6 through its C-terminal coiled-coil domain.Knockdown of SEPT2, SEPT6, and SEPT7 in causes actin stress fibers to disintegrate and cells to lose polarity. Septins, SOCS7, and NCK1 are part of a signaling pathway that couples regulation of the DNA damage response to the cytoskeleton.
Purification Method	Protein G purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	SEPT2 can hetero-oligomerize with SEPT6 and SEPT7 to form filaments. SEPT2 interacted with SEPT6 through its C-terminal coiled-coil domain.Knockdown of SEPT2, SEPT6, and SEPT7 in causes actin stress fibers to disintegrate and cells to lose polarity. Septins, SOCS7, and NCK1 are part of a signaling pathway that couples regulation of the DNA damage response to the cytoskeleton.
Cellular Localization	Cytoskeleton, Membrane

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 7/24/2025

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