Comparison

Anti-CD86 Mouse mAb

Item no. PTM-5570
Manufacturer PTM Biolabs
Amount 100 ul
Category
Type Antibody Monoclonal
Format Lyophilized powder
Applications FC, ICC
Clone 12495
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Conjugate/Tag Unconjugated
Citations Siyue Chen, et al. Bruton's tyrosine kinase inhibition suppresses pathological retinal angiogenesis. BRITISH JOURNAL OF PHARMACOLOGY, 2024. https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.17344.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD28LG2
Shipping Condition Room temperature
Available
Manufacturer - Type
Primary Antibodies
Manufacturer - Applications
ICC/IF, FC
Manufacturer - Category
Uncategorized
Manufacturer - Targets
CD86
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Cell Biology, Immunology
Product description
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG1 produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.
Purification Method
Protein G purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Also involved in the regulation of B cells function, plays a role in regulating the level of IgG1 produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.
Cellular Localization
Membrane

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
available

Delivery expected until 9/25/2025 

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