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Anti-CXCR4 Mouse mAb

Anti-CXCR4 Mouse mAb

Item no.	PTM-5771
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized powder
Applications	FC
Clone	11541
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CXC-R4, FB22, Fusin, HM89, LCR1, LESTR, LAP-3, NPYRL, SDF-1 receptor, CD184
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	CXCR4
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	43
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Immunology, Microbiology, Neuroscience, Stem Cells, Metabolism
Product description	C-X-C chemokine receptor type 4 (CXCR-4), also known as CD184, is a protein that in humans is encoded by the CXCR4 gene. The protein is a CXC chemokine receptor. CXCR-4 is an alpha-chemokine receptor specific for stromal-derivedfactor-1, a molecule endowed with potent chemotactic activity for lymphocytes. CXCR4 is one of several chemokine co-receptors that HIV can use to infect CD4+ T cells. HIV isolates that use CXCR4 are traditionally known as T-cell tropic isolates. CXCR4 is present in newly generated neurons during embryogenesis and adult life where it plays a role in neuronal guidance. The levels of the receptor decrease as neurons mature. CXCR4 gene mutant mice have aberrant neuronal distribution. This has been implicated in disorders such as epilepsy.
Purification Method	Protein G purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	C-X-C chemokine receptor type 4 (CXCR-4), also known as CD184, is a protein that in humans is encoded by the CXCR4 gene. The protein is a CXC chemokine receptor. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived-factor-1, a molecule endowed with potent chemotactic activity for lymphocytes. CXCR4 is one of several chemokine co-receptors that HIV can use to infect CD4+ T cells. HIV isolates that use CXCR4 are traditionally known as T-cell tropic isolates. CXCR4 is present in newly generated neurons during embryogenesis and adult life where it plays a role in neuronal guidance. The levels of the receptor decrease as neurons mature. CXCR4 gene mutant mice have aberrant neuronal distribution. This has been implicated in disorders such as epilepsy.
Cellular Localization	Membrane, Lysosome, Cell junction

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 10/2/2025

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