Anti-Huntingtin Mouse mAb

Uncategorized

Store at -20°C. Avoid freeze/thaw cycles.

Anti-Huntingtin Mouse mAb

PBS, Glycerol, BSA

Recombinant Monoclonal

Huntingtin (Htt), is the protein coded for by the HTT gene, also known as the IT15 (interesting transcript 15) gene. Mutated HTT is the cause of Huntington's disease (HD), and has been investigated for this role and also for its involvement in long-term memory storage. It is variable in its structure, as the many polymorphisms of the gene can lead to variable numbers of glutamine residues present in the protein. In its wild-type (normal form), it contains 6-35 glutamine residues. However, in individuals affected by Huntington's disease (an autosomal dominant genetic disorder), it contains more than 36 glutamine residues (highest reported repeat length is about 250). Its commonly used name is derived from this disease.