Anti-PKC alpha Rabbit mAb

Uncategorized

Store at -20°C. Avoid freeze/thaw cycles.

Anti-PKC alpha Rabbit mAb

PBS, Glycerol, BSA

Recombinant Monoclonal

Protein kinase C alpha (PKC alpha) is an enzyme that is encoded by the PRKCA gene in human. PKC is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca2+ handling in myocytes. PKC alpha is a specific member of the protein kinase family. These enzymes are characterized by their ability to add a phosphate group to other proteins, thus changing their function.