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Anti-HIP1 Mouse mAb

Anti-HIP1 Mouse mAb

Item no.	PTM-6306
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized powder
Applications	WB, ICC
Clone	JMMR-2033
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Huntingtin-interacting protein 1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	WB, ICC/IF
Manufacturer - Category	Uncategorized
Manufacturer - Targets	HIP1
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Neuroscience
Product description	HIP1 plays a role in clathrin-mediated endocytosis and trafficking, which is involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. It regulates presynaptic nerve terminal activity. It can enhance androgen receptor (AR)-mediated transcription and may act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. It can bind 3-phosphoinositides (via ENTH domain). It is required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	HIP1 plays a role in clathrin-mediated endocytosis and trafficking, which is involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. It regulates presynaptic nerve terminal activity. It can enhance androgen receptor (AR)-mediated transcription and may act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. It can bind 3-phosphoinositides (via ENTH domain). It is required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
Cellular Localization	Cytoplasm, Nucleus

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 2/19/2026

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