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Anti-ROCK1 Mouse mAb

Anti-ROCK1 Mouse mAb

Item no.	PTM-6454
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Monoclonal
Format	Lyophilized powder
Applications	WB, IHC-P
Clone	JMMR-2495
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
Citations	Wang Ping, et al. Dissecting T cell heterogeneity in esophageal squamous-cell carcinoma reveal the potential role of LAIR2 in anti-tumor immunity. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2023. https://academic.oup.com/cei/advance-article-abstract/doi/10.1093/cei/uxad073/7221711.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	p160 ROCK-1,p160ROCK,ROCK-I
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	ROCK1
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Signal Transduction, Cell Biology, Cancer
Product description	ROCK1 is a protein serine/threonine kinase, also known as rho-associated, coiled-coil-containing protein kinase 1. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation. ROCK1 plays a role in cancer and in particular cell motility, metastasis, and angiogenesis. ROCK1 is also a key regulator of actin-myosin contraction, stability, and cell polarity.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	ROCK1 is a protein serine/threonine kinase, also known as rho-associated, coiled-coil-containing protein kinase 1. ROCK1 is a major downstream effecter of the small GTPase RhoA and is a regulator of the actomyosin cytoskeleton which promotes contractile force generation. ROCK1 plays a role in cancer and in particular cell motility, metastasis, and angiogenesis. ROCK1 is also a key regulator of actin-myosin contraction, stability, and cell polarity.
Cellular Localization	Cytoplasm, Cytoskeleton, Membrane

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 2/19/2026

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