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Anti-Phospho-PTP1B (Ser352) Rabbit pAb

Anti-Phospho-PTP1B (Ser352) Rabbit pAb

Item no.	PTM-6956
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PTPN1
Shipping condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	PTP1B
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Signal Transduction, Cardiovascular Biology
Product description	Protein-tyrosine phosphatase 1B (PTP1B) is the original member of the protein tyrosine phosphatase (PTP) family of proteins. PTP1B is highly expressed in insulin-responsive tissues and negatively regulates insulin, as well as integrin, through dephosphorylation of phosphotyrosine residues. PTP1B knockout mice show resistance to dietary weight gain and enhanced insulin sensitivity, suggesting a possible role in treatment of obesity as well as type 2 diabetes.
Purification Method	Protein A and immunogen affinity purified
Formula	PBS, Glycerol, BSA
PTM	Phospho
Modification Site	Ser352
Clonality	Polyclonal
Background	Protein-tyrosine phosphatase 1B (PTP1B) is the original member of the protein tyrosine phosphatase (PTP) family of proteins. PTP1B is highly expressed in insulin-responsive tissues and negatively regulates insulin, as well as integrin, through dephosphorylation of phosphotyrosine residues. PTP1B knockout mice show resistance to dietary weight gain and enhanced insulin sensitivity, suggesting a possible role in treatment of obesity as well as type 2 diabetes.
Cellular Localization	Endoplasmic reticulum membrane

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 7/24/2025