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Anti-SF2 Rabbit pAb

Anti-SF2 Rabbit pAb

Item no.	PTM-6972
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SRSF1,ASF,SF2,SF2P33,SFRS1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	SF2
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Epigenetics
Product description	SF2 is named as ASF, is a member of the Ser-Arg-rich (SR) protein family of highly conserved nuclear phosphoproteins involved in pre-mRNA splicing. Besides its role in nuclear pre-mRNA splicing, SF2 has been shown to shuttle between the nucleus and cytoplasm, suggesting additional roles in mRNA transport and cytoplasmic events. SF2 associates with translating ribosomes and stimulates translation. It also activates translation initiation by suppressing the activity of 4E-BP1, which is mediated by SF2 association with mTOR and the phosphatase PP2A. More recent studies have demonstrated a role for SF2 in microRNA processing.
Purification Method	Protein A and immunogen affinity purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Polyclonal
Background	SF2 is named as ASF, is a member of the Ser-Arg-rich (SR) protein family of highly conserved nuclear phosphoproteins involved in pre-mRNA splicing. Besides its role in nuclear pre-mRNA splicing, SF2 has been shown to shuttle between the nucleus and cytoplasm, suggesting additional roles in mRNA transport and cytoplasmic events. SF2 associates with translating ribosomes and stimulates translation. It also activates translation initiation by suppressing the activity of 4E-BP1, which is mediated by SF2 association with mTOR and the phosphatase PP2A. More recent studies have demonstrated a role for SF2 in microRNA processing.
Cellular Localization	Cytoplasm

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 2/19/2026

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