« Back
Home /
Anti-Metabotropic Glutamate Receptor 2 / MGLUR2 Rabbit pAb

Anti-Metabotropic Glutamate Receptor 2 / MGLUR2 Rabbit pAb

Item no.	PTM-7004
Manufacturer	PTM Biolabs
Amount	100 ul
Category	Antibodies Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized powder
Applications	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	mGluR2,GRM2,GPRC1B
Shipping Condition	Room temperature
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	Metabotropic Glutamate Receptor 2 / MGLUR2
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Neuroscience
Product description	Metabotropic glutamate receptor 2 (mGluR2) is a class C G protein-coupled receptor for the neurotransmitter glutamate in the mammalian brain. Unlike ionotropic receptors, metabotropic receptors do not form an ion channel pore themselves but are indirectly linked to ion channels. While mGluR1 and mGluR5 activate phospholipase C, mGluR2, mGluR3, mGluR4, and mGluR6 are coupled to the inhibitory G protein Gα(i/o) and inhibit adenylyl cyclase (AC) activity. Research studies have suggested that mGluR2/3 receptors may be potential targets for the treatment of Schizophrenia. Furthermore, mGluR2 interacts with the 5HT2A serotonin receptor to form a heterocomplex in the brain. This complex is a potential pharmacological target for hallucinogenic drugs.
Purification Method	Protein A and immunogen affinity purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Polyclonal
Background	Metabotropic glutamate receptor 2 (mGluR2) is a class C G protein-coupled receptor for the neurotransmitter glutamate in the mammalian brain. Unlike ionotropic receptors, metabotropic receptors do not form an ion channel pore themselves but are indirectly linked to ion channels. While mGluR1 and mGluR5 activate phospholipase C, mGluR2, mGluR3, mGluR4, and mGluR6 are coupled to the inhibitory G protein Gα(i/o) and inhibit adenylyl cyclase (AC) activity. Research studies have suggested that mGluR2/3 receptors may be potential targets for the treatment of Schizophrenia. Furthermore, mGluR2 interacts with the 5HT2A serotonin receptor to form a heterocomplex in the brain. This complex is a potential pharmacological target for hallucinogenic drugs.
Cellular Localization	Cell membrane

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 2/19/2026

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer