ACE (ADCP, DCP1, Angiotensin-converting enzyme, Dipeptidyl carboxypeptidase I, Kininase II, Angiotensin-converting enzyme, soluble form)

Antibodies / Antibodies-ACE

-20°C

Supplied as a liquid, 0.09% sodium azide.

ACE Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human ACE.

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Applications:
Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1, 000
Western Blot: 1:500~16000

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.