DUOX2, ID (DUOX2, LNOX2, THOX2, Dual oxidase 2, Large NOX 2, Long NOX 2, NADH/NADPH thyroid oxidase p138-tox, NADPH oxidase/peroxidase DUOX2, NADPH thyroid oxidase 2, Thyroid oxidase 2, p138 thyroid oxidase)

Antibodies / Antibodies-Enzymes, Oxidase

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 513-542 in the c-terminal region of human DUOX2, UniProt Accession #Q9NRD8

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain.

Applications:
Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:1000
Indirect Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.