LARP7, CT (LARP7, La-related protein 7, La ribonucleoprotein domain family member 7, P-TEFb-interaction protein for 7SK stability)

Antibodies / Antibodies-Nuclear Proteins

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-556 amino acids from the C-terminal region of human LARP7.

LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1, 000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.