Eng (Endoglin, Cell Surface MJ7/18 Antigen, CD105, Edg, AI528660, AI662476, S-endoglin)

Antibodies / Antibodies-CD Markers

-20°C

Supplied as a lyophilized powder from PBS, pH 7.2. No preservative added. Reconstitute with sterile dH2O or PBS.

Recombinant protein corresponding to mouse soluble CD105.

Endoglin, also known as CD105, is a Type I integral membrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated, cytoplasmic tail. Two splice variants of human endoglin, the S endoglin and L-endoglin that differ in the length of their cytoplasmic tails have been identified. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta.

Applications:
Suitable for use in Flow Cytometry, ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 3-20ug/ml
ELISA: 1-15ug/ml
Western Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.