Cyclin D1 (BCL1, U21B31, D11S287, , PRAD1, B Cell CLL/lymphoma 1, G1/S-specific cyclin D1, parathyroid adenomatosis 1, B Cell lymphoma 1 protein, BCL-1 oncogene, PRAD1 oncogene)

Antibodies / Antibodies-Cyclin

4°C/-20°C

Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Recombinant human cyclin D1 protein.

D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1(CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

UniProt Number:
Human(P24385), Mouse(P25322), Rat(P39948)

Gene ID:
CCND1

Applications:
Suitable for use in Western Blot, Immunohistochemistry (Paraffin and Frozen), and Immunocytochemistry.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Handling:
Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.