C-FOS (aa283-295) (Activator protein 1,AP-1,Cellular oncogene C-FOS,FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS),FBJ murine osteosarcoma viral oncogene homolog,FOS,G0/G1 switch regulatory protein

Antibodies / Antibodies-Oncoproteins

-20°C

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Synthetic peptide corresponding to aa283-295 from sequence C-SETARSVPDMDLS, at the internal region of the protein sequence according to NP_005243.1. Species sequence homology: feline, canine, porcine and bovine

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

Applications:
Suitable for use in Peptide ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Peptide ELISA: 1:128, 000
Western Blot: 0.3-1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.