SLC6A4 (5HT transporter, 5HTT, 5-HTT, 5-HTTLPR, 5-hydroxytryptamine transporter, hSERT, HTT, Na+/Cl- dependent serotonin transporter, OCD1, SERT, Sodium-dependent serotonin transporter, Solute carrier family 6 (neurotransmitter transporter, sero

Antibodies / Antibodies-Transport Proteins

-20°C

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Synthetic peptide corresponding to aa605-618 from sequence C-KERIIKSITPETPT, at the C-terminus of the protein sequence according to NP_001036.1. Species sequence homology: human, rat and bovine

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Applications:
Suitable for use in Peptide ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Peptide ELISA: 1:32, 000
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.