Comparison

MCAM (CD146, CD146 Antigen, Gicerin, Melanoma Adhesion Molecule, MUC18, p1h12)

Item no. USB-215722
Manufacturer United States Biological
Amount 50 ug
Category
Type Antibody Monoclonal
Format Liquid
Applications WB, FC, IHC, ELISA
Clone 6C3E6
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Purity Purified
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Shipping Condition Cool pack
Available
Manufacturer - Type
Mab
Manufacturer - Category
Antibodies / Antibodies-CD Markers
Shipping Temperature
Blue Ice
Storage Conditions
-20°C
Grade
Purified
Form
Supplied as a liquid in PBS, 0.05% sodium azide, 0.5% protein stabilizer.
EU Commodity Code
30021010
Immunogen
Recombinant fragment corresponding to aa84-189 from human MCAM.
Specificity
Recognizes human MCAM.
Description
MCAM (also termed CD146 or MUC18) is a cell-adhesion molecule belonging to the immunoglobulin gene superfamily. It mediates cell-cell interaction through heterophilic Mel-CAM/ligand adhesion. MCAM has been shown to expressed widely in normal and neoplastic human tissues. MUC18 expression is increased during prostate cancer initiation (high grade PIN) and progression to carcinoma, and in metastatic cell lines and metastatic carcinoma.

Applications:
Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: 1:200-1:400
ELISA: 1:10, 000
Western Blot: 1:500-1:2000
Immunohistochemistry(Paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close