HSP60 (HSPD1,Heat Shock 60kD Protein 1 (Chaperonin),CPN60,GROEL,HLD4,HSP-60,HSP60,HSP65,HuCHA60,SPG13,60kD Chaperonin,60kD Heat Shock Protein,Mitochondrial,P60 Lymphocyte Protein ,Chaperonin 60,Heat Shock Protein 65,Mito

Antibodies / Antibodies-Heat Shock Proteins

-20°C

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Synthetic peptide corresponding to C-NLEDVQPHDLGK of human HSP60 (NP_002147.2). Species sequence homology: canine, bovine

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

Applications:
Suitable for use in ELISA, Western Blot. Other applications not tested.

Recommended Dilution:
Peptide ELISA: 1:64, 000
Western Blot: 0.01-0.3ug/ml, ~60kD band observed in Human and Pig Heart, Kidney and Liver lysates (calculated MW of 61.1kD according to NP_002147.2).
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.