CD13 (Aminopeptidase N, AP-N, hAPN, Alanyl Aminopeptidase, Aminopeptidase M, AP-M, Microsomal Aminopeptidase, Myeloid Plasma Membrane Glycoprotein CD13, gp150, ANPEP, APN, PEPN)

Antibodies / Antibodies-CD Markers

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Human CD13

CD13 is a 150-170kD type II transmembrane glycoprotein also known as aminopeptidase N, APN, and gp150. This zinc metallopeptidase as a homodimer is expressed on granulocytes, myeloid progenitors, endothelial cells, epithelial cells and subset of granular lymphoid cells. It is not expressed on platelets or erythrocytes. CD13 is thought to be involved in the metabolism of many regulatory peptides and functions in antigen processing and the cleavage of chemokines such as MIP-1. CD13 serves as the cellular receptor for Coronavirus.

Applications:
Suitable for use in Flow Cytometry, Blocking and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Flow Cytometry: ≤2ug/10e5 cells in 100ul
Immunohistochemistry: acetone-fixed, frozen tissue sections
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.