CCK4, NT (Tyrosine-protein Kinase-like 7, Colon Carcinoma Kinase-4, CCK-4, Protein-tyrosine Kinase 7, PTK7)

Antibodies / Antibodies-Tyrosine Kinases

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide.

Synthetic peptide selected from the N-terminal region of human PTK7 (KLH).

PTK7 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, and it is weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. Expression is also detected in erythroleukemia cells.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:1, 000
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.