Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2, Fragile X Mental Retardation Syndrome Related Protein 2, Fragile X Mental Retardation Gene Autosomal Homolog 2, Fragile X Mental Retardation 1-like 2, FMR1L2)

Antibodies / Antibodies-Disease Markers

-20°C

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Recombinant C-terminal fragment of human FXR2 (residues 414-658).

Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:2, 00. A band is seen at ~80kD. Theoretical MW is 74kD.
Optimal dilutions to be determined by the researcher.

Localization: Cytoplasmic
Gene Symbol: FXR2
Entrez:9513 (Human), 23879 (Mouse)
Swiss Prot: P51116 (Human)

Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.