IL6ST,phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta,IL-6R-beta,Interleukin-6 Signal Transducer,Membrane Glycoprotein 130,gp130,CDw130,Oncostatin-M Receptor Subunit alpha,CD130,IL-6 Receptor Subunit beta,IL

Antibodies / Antibodies-Interleukin

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide.

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa889-918 surrounding Y905 of human IL6ST, UniProt Accession #NP_002175.2, P40189
Cellular Localization: Isoform 1: Cell membrane; Single-pass type 1 membrane protein

IL6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein.

Applications:
Suitable for use in Dot Blot. Other applications not tested.

Recommended Dilutions:
Dot Blot: 1:500
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.