PAEL Receptor 37 Like 1 (GPR37L1, G-protein coupled receptor 37, ETBR-LP-1, Endothelin B receptor-like protein 1, PAELR, Parkin-associated endothelin receptor-like receptor)

Antibodies / Antibodies-G Protein Receptors

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide.

Synthetic peptide corresponding to extracellular domain of human GPR37L1 at N-terminal (KLH).

GPR37L1 (G-protein coupled receptor 37-like 1), also called ETBR-LP-2 (endothelin B receptor-like protein 2), is a 481aa, orphan 7-transmembrane receptor with calculated molecular weight of 53kD. GPR37L1 is expressed in cerebellar Bergmann glia, cerebral cortex and internal capsule fibers in the central nervous system. It shows 39%aa identity with GPR37, a neuronal protein that accumulates in juvenile Parkinson’s disease neurons under endoplasmic reticulum stress. GPR37L1 does not bind known endothelin B family members. The extracellular portions of human and mouse GPR37L1 share 85%aa identity.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.