Proprotein Convertase Subtilisin Kexin 9,CT (Proprotein Convertase Subtilisin/kexin Type 9,PCSK9,FH3,Hypercholesterolemia Autosomal Dominant 3,HCHOLA3,LDLCQ1,Neural Apoptosis Regulated Convertase 1,NARC1,NARC-1,PC9,Propr

Antibodies / Antibodies-Enzymes

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide.

Synthetic peptide selected from the C-terminal region (between corresponding to a portion of amino acids within aa487 and 516) of human PCSK9 (conjugated to KLH).

PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.

Applications:
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1, 000
Immunohistochemistry: :50-1:100
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.