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Anti-Mouse/Rat IL-17A APC

Anti-Mouse/Rat IL-17A APC

Item no.	73812-80-50
Manufacturer	BioGems
Amount	50 ug
Category	Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Primary Antibodies
Type	Antibody
Applications	FC
Clone	17B7
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	APC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.
Storage Temperature	4C
Concentration	0.2 mg/mL
Preparation and Storage	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

73812-80-50-datasheet.pdf

73812-80-50-safety-datasheet.pdf