Comparison

Anti-Human IL-17A PE

Item no. 73821-60-25
Manufacturer BioGems
Amount 25 tests
Category
Type Antibody
Applications FC
Clone 64Dec17
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Conjugate/Tag PE
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Description
The 64DEC17 monoclonal antibody specifically binds to human IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells. The 64DEC17 is a neutralizing antibody.
Storage Temperature
4C
Concentration
5 uL (0.25 ug)/test
Preparation and Storage
The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 tests
Available: In stock
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