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Anti-GAD67 Antibody

Anti-GAD67 Antibody

Item no.	75-507
Manufacturer	Antibodies Incorporated
Amount	100 uL
Category	Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Primary Antibodies
Type	Antibody Primary
Format	Liquid
Applications	WB, IHC, ICC
Clone	L127/8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	GAD67, Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform, GAD1, GAD and DCE1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	GAD67
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	70 kDa
Manufacturer - Research Area	Cell Markers, Neuronal Markers
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-594 (full-length) of human GAD67 (accession number Q99259) produced recombinantly in E. Coli
Immunogen Species	Human
Description	Our Anti-GAD67 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L127/8. It detects human, mouse, and rat GAD67, and is purified by Protein A chromatography. It is great for use in AT, IHC, ICC, WB.
Target Description	Glutamate decarboxylase 1, GAD67 or GAD1 is a member of the group II decarboxylase family and catalyzes the production of GABA from L-glutamic acid. GAD67 is expressed in brain (throughout the cell), in insulin producing ßcells of the pancreas, and several non-neuronal tissues during development. Alterations in GAD67 have been shown to lead to pyridoxine dependency with seizures. Other disorders associated with GAD67 are Cerebral Palsy, Spastic Quadriplegic, 1 and Inherited Congenital Spastic Tetraplegia.
Clonality	Monoclonal
Manufacturer - Specificity	Cross-reacts with GAD25 Does not cross-react with GAD44 or GAD65/GAD2
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Quality Control: Application	WB Brain
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our GAD67 mouse monoclonal primary antibody from hybridoma clone L127/8. It is great in AT, IHC, ICC, WB and is purified by Protein A chromatography.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 uL

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Delivery expected until 10/30/2025

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