MonoRab Human PD-L1 Antibody (X228), mAb, Rabbit

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
IHC: 1-5 ug/ml
Other applications: user-optimized

4°C

Programmed cell death 1 ligand 1 is one of the two ligands of PD-1. PD-L1 is expressed on macrophages, T cells, B cells, NK cells, DCs and some cancer cell surface. Binding of PD-1 with PD-L1 could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-L1 is an important immune checkpoint and popular target for therapeutic antibodies against many cancers.
GenScript MonoRab Human PD-L1 Antibody (X228), mAb, Rabbitis produced from cell culture in vitro under conditions free from animal-derived components.