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Anti-PINX1 Picoband Antibody

Anti-PINX1 Picoband Antibody

Item no.	ABC-ABO12186
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Lyophilized
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PINX1, Liver-related putative tumor suppressor, LPTL, LPTS, Pin2-interacting protein X1, PIN2/TERF1-interacting telomerase inhibitor 1, Protein 67-11-3, TRF1-interacting protein 1
Available
Primary Accession	Q96BK5
Application	WB
Clonality	Polyclonal
Gene ID	54984
Reactivity	H
Legend image 1	Anti- PINX1 Picoband antibody, ABO12186, Western blottingAll lanes: Anti PINX1 (ABO12186) at 0.5ug/mlLane 1: Human Placenta Tissue Lysate at 50ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: HUT Whole Cell Lysate at 40ugLane 4: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 37KDObserved bind size: 37KD
Type image 1	WB
Dilution image 1	0.1-0.5 µg/ml
Calculated MW	37035
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description	Rabbit IgG polyclonal antibody for PIN2/TERF1-interacting telomerase inhibitor 1(PINX1) detection. Tested with WB in Human.
Protein Function	Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. .
Subcellular Localization	Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE.
Tissue Specificity	Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.
Protein Name	PIN2/TERF1-interacting telomerase inhibitor 1
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human PINX1 (54-83aa DHIKVQVKNNHLGLGATINNEDNWIAHQDD), different from the related mouse and rat sequences by three amino acids.
Purification	Immunogen affinity purified.
Cross Reactivity	No cross reactivity with other proteins
Storage	At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities	Belongs to the PINX1 family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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