Comparison

Goat Anti-FTL Antibody

Item no. ABC-AF1447a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, IHC, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products FTL, Ferritin light chain, Ferritin L subunit
Available
Primary Accession
P02792
Antigen Type
Synthetic Peptide
Application
WB, IHC, E, EIA
Bio Background
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.
Bio References
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer. Wang X, et al. PLoS One, 2010 Aug 3. PMID 20689807.
Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030.
Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070.
Toluene diisocyanate (TDI) regulates haem oxygenase-1/ferritin expression: implications for toluene diisocyanate-induced asthma. Kim SH, et al. Clin Exp Immunol, 2010 Jun. PMID 20345975.
Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. Luscieti S, et al. J Biol Chem, 2010 Apr 16. PMID 20159981.
Clonality
Polyclonal
Gene ID
2512
Gene Name
FTL
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF1447a (0.05 µg/ml) staining of Human Placenta lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Legend image 2
AF1447a (3.8 µg/ml) staining of paraffin embedded Human Brain Cortex. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Type image 2
IHC
Legend image 3
AF1447a (1.5ug/ml) as the reporter with EB002025 as the capture rabbit antibody (5ug/ml).
Type image 3
EIA
Other Accession
NP_000137; 2512; 14325 (mouse); 29292 (rat);
Predicted
M, Rat, Dog, Cow
Concentration (mg/ml)
100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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