Comparison

Goat Anti-LAT1 Antibody

Item no. ABC-AF1616a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products LAT, pp36, Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, p36-38
Available
Primary Accession
O43561
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Bio References
New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.
Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.
PI3 kinase function is vital for the function but not formation of LAT-mediated signaling complexes. Cruz-Orcutt N, et al. Mol Immunol, 2009 Jul. PMID 19427038.
The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage. Shen S, et al. J Immunol, 2009 May 1. PMID 19380807.
Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, et al. J Hum Genet, 2009 Jun. PMID 19343046.
Clonality
Polyclonal
Gene ID
27040
Gene Name
LAT
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H, M, Rat
Legend image 1
AF1616a (0.01 µg/ml) staining of peripheral blood mononucleocytes lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Other Accession
NP_001014988; 27040;
Concentration (mg/ml)
100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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