Comparison

Goat Anti-Syntrophin (alpha 1) Antibody

Item no. ABC-AF2059a
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products SNTA1, Syntrophin-1, SNT1, TACIP1, Alpha-1-syntrophin, 59 kDa dystrophin-associated protein A1 acidic component 1, Pro-TGF-alpha cytoplasmic domain-interacting protein 1
Available
Primary Accession
Q13424
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
Bio References
Alpha1-syntrophin mutations identified in sudden infant death syndrome cause an increase in late cardiac sodium current. Cheng J, et al. Circ Arrhythm Electrophysiol, 2009 Dec. PMID 20009079.
alpha-1-syntrophin mutation and the long-QT syndrome: a disease of sodium channel disruption. Wu G, et al. Circ Arrhythm Electrophysiol, 2008 Aug. PMID 19684871.
Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex. Ueda K, et al. Proc Natl Acad Sci U S A, 2008 Jul 8. PMID 18591664.
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Olsen JV, et al. Cell, 2006 Nov 3. PMID 17081983.
Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays. Stiffler MA, et al. J Am Chem Soc, 2006 May 3. PMID 16637659.
Clonality
Polyclonal
Gene ID
6640
Gene Name
SNTA1
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H, M, Rat
Legend image 1
AF2059a (0.01 µg/ml) staining of Human Muscle lysate (35 µg protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Other Accession
NP_003089; 6640; 20648 (mouse);
Predicted
Pig, Dog, Cow
Concentration (mg/ml)
100ug/200ul

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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