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p21WAF1 (Tumor Suppressor Protein) Antibody - With BSA and Azide

p21WAF1 (Tumor Suppressor Protein) Antibody - With BSA and Azide

Item no.	ABC-AH10996-U0100
Manufacturer	Abcepta
Amount	100 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, FC, IF, IHC
Clone	CIP1/823
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	p21, CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, MDA-6
Available
Primary Accession	P38936
Application	WB, IHC, IF, FC
Bio Background	This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Bio References	Harper, J.W., et al. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816. \|
Clonality	Monoclonal
Gene ID	1026
Gene Name	CDKN1A
Subtitle	Mouse Monoclonal Antibody [Clone CIP1/823 ]
Reactivity	H
Legend image 1	Formalin-fixed, paraffin-embedded human Lung Squamous Cell Carcinoma (SCC) stained with p21 Monoclonal Antibody (CIP1/823).
Type image 1	IHC
Legend image 2	Formalin-fixed, paraffin-embedded human Bladder Carcinoma stained with p21 Monoclonal Antibody (CIP1/823).
Type image 2	IHC
Other Accession	1026, 370771
	Clone: CIP1/823

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/4/2025

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