Comparison

gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) Antibody - With BSA and Azide

Item no. ABC-AH12312-U0100
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications FC, IF, IHC
Clone HMB45 + PMEL/783
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products SILV, PMEL, D12S53E, PMEL17, Melanocyte protein PMEL, ME20-M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, M-alpha, P26, ME20M, 95 kDa melanocyte-specific secreted glycoprotein, Secreted melanoma-associated ME20 antigen, ME20-S, ME20S, M-beta
Available
Primary Accession
P40967
Application
IHC, IF, FC
Bio Background
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
Bio References
Gown AM, et. al. American Journal of Pathology, 1986, 123(2):195-203
Clonality
Monoclonal
Gene ID
6490
Gene Name
PMEL
Subtitle
Mouse Monoclonal Antibody [Clone HMB45 + PMEL/783 ]
Reactivity
H
Legend image 1
Formalin-fixed, paraffin-embedded human Melanoma stained with gp100 / Melanosome Monoclonal Antibody (HMB45 + PMEL/783).
Type image 1
IHC
Legend image 2
Formalin-fixed, paraffin-embedded human Testis stained with gp100 / Melanosome Monoclonal Antibody (HMB45 + PMEL/783).
Type image 2
IHC
Other Accession
6490, 95972
Clone: HMB45 + PMEL/783

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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