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ZAP70 (Chronic Lymphocytic Leukemia Marker) Antibody - With BSA and Azide

ZAP70 (Chronic Lymphocytic Leukemia Marker) Antibody - With BSA and Azide

Item no.	ABC-AH12545-U0020
Manufacturer	Abcepta
Amount	20 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	FC, IF, IHC
Clone	ZAP70/528 + 2F3.2
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	ZAP70, SRK, Tyrosine-protein kinase ZAP-70, 70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, 2.7.10.2
Available
Primary Accession	P43403
Application	IHC, IF, FC
Bio Background	ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells.?Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.?Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.
Bio References	Iwashima M, Irving BA, van Oers NSC, Chan AC, Weiss A. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science 1994; 263:1136-9
Clonality	Monoclonal
Gene ID	7535
Gene Name	ZAP70
Subtitle	Mouse Monoclonal Antibody [Clone ZAP70/528 + 2F3.2 ]
Reactivity	H
Legend image 1	Formalin-fixed, paraffin-embedded human Tonsil stained with ZAP70 Monoclonal Antibody (ZAP70/528 + 2F3.2).
Type image 1	IHC
Other Accession	7535, 234569
	Clone: ZAP70/528 + 2F3.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ug

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Delivery expected until 10/2/2025

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